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Saffron is generally considered safe when used in normal food amounts. However, consuming large amounts of saffron can lead to a variety of side effects.

Saffron is POSSIBLY SAFE for most people when taken by mouth as a medicine for up to 6 weeks. Some possible side effects include dry mouth, anxiety, dizziness, drowsiness, nausea, change in appetite, and headache. Allergic reactions can occur in some people.

Taking large amounts of saffron by mouth is POSSIBLY UNSAFE. High doses can cause poisoning, including yellow appearance of the skin, eyes, and mucous membranes; vomiting; dizziness; bloody diarrhea; bleeding from the nose, lips, and eyelids; numbness; and other serious side effects. Doses of 12-20 grams can cause death.

ALLERGIC REACTIONS

Saffron can cause allergic reactions in some people. Symptoms of an allergic reaction may include itching, rash, swelling, or difficulty breathing.

NAUSEA AND VOMITING

Consuming large amounts of saffron can cause stomach upset, including nausea and vomiting.

HEADACHE

Some people may experience headaches after consuming saffron.

DIZZINESS

Saffron may cause dizziness or lightheadedness in some people.

DRY MOUTH

Saffron can cause a dry mouth sensation in some individuals.

CHANGES IN MOOD OR BEHAVIOR

Some people have reported feeling euphoric or having changes in mood after consuming large amounts of saffron.

HYPOTENSION

Consuming high doses of saffron can lower blood pressure and lead to hypotension, which may cause dizziness or fainting.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Taking saffron by mouth in amounts larger than what is normally found in food is LIKELY UNSAFE. Larger amounts of saffron can make the uterus contract and might cause a miscarriage.Not enough is known about the safety of using saffron during breast-feeding. Stay on the safe side and avoid use.

Bipolar disorder: Saffron seems to be able to affect mood. There is a concern that it might trigger excitability and impulsive behavior (mania) in people with bipolar disorder. Don't use saffron if you have this condition.

Allergies to Lolium, Olea (includes olive), and Salsola plant species: People who are allergic to these plants might also be allergic to saffron.

Heart conditions: Saffron might affect how fast and how strong the heart beats. Taking large amounts of saffron might worsen some heart conditions.

Low blood pressure: Saffron might lower blood pressure. Taking saffron might make blood pressure become too low in people with low blood pressure.

It's important to note that these side effects are typically associated with high doses of saffron, and most people won't experience them when using saffron in normal food amounts. If you experience any of these side effects after consuming saffron, stop using it and seek medical attention if necessary.